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Top Python projects on GitHub
11,883 Python repositories with 1,000+ stars, ranked by stars.
Repository
Stars
Language
License
Activity
101
pathwaycom/serviette
A no-code RAG server that keeps answers in sync with your documents. Works with 8 vector databases. Built on Pathway.
★ 58.8k
Python
MIT
Active
102
karpathy/nanochat
The best ChatGPT that $100 can buy.
★ 58.7k
Python
MIT
Active
103
FoundationAgents/OpenManus
No fortress, purely open ground. OpenManus is Coming.
★ 58.7k
Python
MIT
Active
104
ultralytics/yolov5
Ultralytics YOLOv5 in PyTorch for object detection, instance segmentation, classification, training, and export.
★ 58.2k
Python
AGPL-3.0
Active
105
blader/humanizer
Agent skill that removes signs of AI-generated writing from text
★ 58k
Python
MIT
Active
106
jamiepine/voicebox
The open-source AI voice studio. Clone, dictate, create.
★ 57.9k
Python
MIT
Active
107
ayghri/i-have-adhd
A skill to stop your coding agent from burying the answer. ADHD-friendly output.
★ 57.7k
Python
MIT
Active
108
zylon-ai/private-gpt
Complete API layer for private AI applications on local models: RAG, skills, tools, MCP, text-to-sql, and more. Works with any OpenAI-compat
★ 57.6k
Python
Apache-2.0
Active
109
deepfakes/faceswap
Deepfakes Software For All
★ 57.6k
Python
GPL-3.0
Active
110
Textualize/rich
Rich is a Python library for rich text and beautiful formatting in the terminal.
★ 57.6k
Python
MIT
Slowing
111
Zie619/n8n-workflows
all of the workflows of n8n i could find (also from the site itself)
★ 57k
Python
MIT
Slowing
112
soimort/you-get
:arrow_double_down: Dumb downloader that scrapes the web
★ 56.9k
Python
Other
Active
113
ageitgey/face_recognition
The world's simplest facial recognition api for Python and the command line
★ 56.8k
Python
MIT
Slowing
114
hesreallyhim/awesome-claude-code
A hand-picked collection of the finest of resources for the most awesome of agents, Claude Code, the undisputed champion of coding companion
★ 56k
Python
Other
Active
115
freqtrade/freqtrade
Free, open source crypto trading bot
★ 55.6k
Python
GPL-3.0
Active
116
odoo/odoo
Odoo. Open Source Apps To Grow Your Business.
★ 55.1k
Python
Other
Active
117
AntonOsika/gpt-engineer
CLI platform to experiment with codegen. Precursor to: https://lovable.dev
★ 55k
Python
MIT
Archived
118
microsoft/VibeVoice
Open-Source Frontier Voice AI
★ 54.9k
Python
MIT
Active
119
bojieli/ai-agent-book
《深入理解 AI Agent:设计原理与工程实践》(李博杰 著)开源主仓库:全书正文、编译版 PDF 与按章配套代码
★ 54.8k
Python
Apache-2.0
Active
120
psf/requests
A simple, yet elegant, HTTP library.
★ 54.5k
Python
Apache-2.0
Active
121
HKUDS/CLI-Anything
"CLI-Anything: Making ALL Software Agent-Native" -- CLI-Hub: https://clianything.cc/
★ 54.5k
Python
Apache-2.0
Active
122
bmad-code-org/BMAD-METHOD
Breakthrough Method for Agile Ai Driven Development
★ 54.3k
Python
Other
Active
123
lllyasviel/Fooocus
Focus on prompting and generating
★ 53.6k
Python
GPL-3.0
Slowing
124
Imbad0202/academic-research-skills
Academic Research Skills for Claude Code: research → write → review → revise → finalize
★ 52.7k
Python
Other
Active
125
K-Dense-AI/scientific-agent-skills
Turn any AI agent into an AI Scientist. The #1 Agent Skills library for science, used by 250,000+ scientists worldwide. 177 ready-to-use val
★ 52.6k
Python
MIT
Active
126
run-llama/llama_index
LlamaIndex is the document processing platform for AI
★ 52.6k
Python
MIT
Active
127
MadsLorentzen/ai-job-search
The job search that runs on your machine. AI job application framework built on Claude Code: evaluate postings, tailor CVs, write cover lett
★ 52.4k
Python
MIT
Active
128
xai-org/grok-1
Grok open release
★ 52.2k
Python
Apache-2.0
Stale
129
charlax/professional-programming
A collection of learning resources for curious software engineers
★ 51.6k
Python
MIT
Active
130
roboflow/supervision
We write your reusable computer vision tools. 💜
★ 51.2k
Python
MIT
Active
131
vectorize-io/hindsight
Hindsight: Agent Memory That Learns
★ 51.2k
Python
MIT
Active
132
pandas-dev/pandas
Flexible and powerful data analysis / manipulation library for Python, providing labeled data structures similar to R data.frame objects, st
★ 50.2k
Python
BSD-3-Clause
Active
133
Aider-AI/aider
aider is AI pair programming in your terminal
★ 49.6k
Python
Apache-2.0
Slowing
134
microsoft/qlib
Qlib is an AI-oriented Quant investment platform that aims to use AI tech to empower Quant Research, from exploring ideas to implementing pr
★ 49.5k
Python
MIT
Active
135
HKUDS/nanobot
Ultra-lightweight, open-source, self-hosted personal AI agent framework in Python with WebUI, tools, memory, MCP, multi-agent workflows, aut
★ 49.1k
Python
MIT
Active
136
Yuan1z0825/nature-skills
符合nature论文学术表达和科研绘图的Skill
★ 49.1k
Python
Apache-2.0
Active
137
SimplifyJobs/Summer2027-Internships
Summer 2027 software engineering, data science, AI, quant, product management, and hardware internship postings. Updated daily by Simplify a
★ 48k
Python
—
Active
138
hiroi-sora/Umi-OCR
OCR software, free and offline. 开源、免费的离线OCR软件。支持截屏/批量导入图片,PDF文档识别,排除水印/页眉页脚,扫描/生成二维码。内置多国语言库。
★ 48k
Python
MIT
Slowing
139
exo-explore/exo
Run frontier AI locally.
★ 48k
Python
Apache-2.0
Active
140
sickn33/agentic-awesome-skills
AAS Core is the local, agent-first control plane for complete catalog discovery, agent-owned selection, stack validation, and planning, back
★ 47.9k
Python
MIT
Active
141
oobabooga/textgen
Open-source desktop app for local LLMs. Text, vision, tool-calling, OpenAI/Anthropic-compatible API. 100% private.
★ 47.7k
Python
AGPL-3.0
Active
142
minimaxir/big-list-of-naughty-strings
The Big List of Naughty Strings is a list of strings which have a high probability of causing issues when used as user-input data.
★ 47.7k
Python
MIT
Stale
143
zhayujie/CowAgent
Open-source personal AI assistant & Agent Harness. Plans tasks, runs tools and skills, self-evolves with memory and knowledge. Multi-agent,
★ 47.5k
Python
MIT
Active
144
apache/airflow
Apache Airflow - A platform to programmatically author, schedule, and monitor workflows
★ 47.2k
Python
Apache-2.0
Active
145
9001/copyparty
Portable file server with accelerated resumable uploads, dedup, WebDAV, SFTP, FTP, TFTP, zeroconf, media indexer, thumbnails++ all in one fi
★ 47.1k
Python
MIT
Active
146
paperless-ngx/paperless-ngx
A community-supported supercharged document management system: scan, index and archive all your documents
★ 46.8k
Python
GPL-3.0
Active
147
coqui-ai/TTS
🐸💬 - a deep learning toolkit for Text-to-Speech, battle-tested in research and production
★ 46.1k
Python
MPL-2.0
Stale
148
streamlit/streamlit
Streamlit — A faster way to build and share data apps.
★ 46k
Python
Apache-2.0
Active
149
vnpy/vnpy
基于Python的开源量化交易平台开发框架
★ 45.9k
Python
MIT
Active
150
mitmproxy/mitmproxy
An interactive TLS-capable intercepting HTTP proxy for penetration testers and software developers.
★ 45.7k
Python
MIT
Active
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